COD: direct a blow at with one's hand or a tool or weapon.All the children now hit the top of the pack to ` turn their card over " . And when I hit those chords really hard , there was none of that fluttering noise and so the rhythm parts became a little spankier sounding . It 's obviously a reasonably-sized practice/small gig amp , but even so the limiter comes in really quickly -- perhaps because my style is to hit the strings really hard . I raised my hand to my eyes wondering how I could have hit it so hard . I hit my pillow so hard that it has looked reproachful ever since . ) Immediately Holmes jumped up and hit the bell-rope hard . I 'm hitting my head repeatedly against something that is n't there and I suppose that that could be a definition of insanity . She flies back and forth in her cage as much as it 's possible , dashing her talons against the bars and hitting her beak against the top . ` Are you admitting I 've hit the nail on the head ? " The idea is to hit atoms head-on with laser beams , slowing them down . I know what we 'll do ; I 'll go up on the dunes and you hit the bell with your bit of wood and we 'll see if I can hear it . Angrily Holmes hit the rock in front of us with his open hand . The matrix is hit with a pulse from a laser beam .For example , the domain from the yeast β ' subunit hit the α-subunits of bacterial DDRPs with Z-scores of 5-7 and RMSD of 2.8-3 Å. Hereinafter we refer to these domains as the α -subunit core-related ( ASCR ) domains .